skeletal muscle — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8242	Sabinene		Others
	Sabinene is a natural product that has antifungal and anti-inflammatory properties		Others
T2S0820	Karanjin		Apoptosis , AMPK
	Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arre...		Apoptosis , AMPK
T23322	SB 452533		TRP/TRPV Channel
	SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).		TRP/TRPV Channel
T22967	MEDICA16	MEDICA 16	GPR , Others , ATP Citrate Lyase
	MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insu...		GPR , Others , ATP Citrate Lyase
T22371	Mivacurium dichloride	Mivacurium chloride	AChR
	Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg...		AChR
T7144	BTS	N-Tosylbenzylamine,N-Benzyl-p-toluenesulfonamide	ATPase , Myosin
	BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .		ATPase , Myosin
T2176	2,3-Butanedione 2-Monoxime	Diacetyl monoxime,2,3-Butanedione-2-monoxime	Akt
	2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.		Akt
T40101	(±)-1,2-Diolein	1,2-Dioleoyl-rac-glycerol	PKC
	(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.		PKC
T67951	JB061		Myosin
	JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle myosin), and >100 μM (Smooth muscle myosin II). It exhibits l...		Myosin
T67952	JB062		Myosin
	JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It se...		Myosin
T4054	Dantrolene sodium hemiheptahydrate	Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,Sodium dantrolene	Calcium Channel , Autophagy
	Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from t...		Calcium Channel , Autophagy
T1459	Cisatracurium besylate	51W89	Adrenergic Receptor , AChR , Autophagy
	Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant for intravenous administration.		Adrenergic Receptor , AChR , Autophagy
T67965	Torbafylline		cAMP , PI3K , PDE
	Torbafylline, a xanthine derivative, is a phosphodiesterase (PDE) inhibitor that attenuates burn-induced protein hydrolysis in rat skeletal muscle through activation of the PDE4/cAMP/EPAC/PI3K/Akt pathway, and inhibits t...		cAMP , PI3K , PDE
T6618	Orphenadrine Citrate	Flexon,Flexoject,Banflex	AChR , iGluR
	Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.		AChR , iGluR
T64851	Phenprobamate	MH 532,Proformiphen,3-Phenylpropyl carbamate
	Phenprobamate (MH 532) is a relaxant that acts on central skeletal muscle and has anticonvulsant and psychostimulant effects.
T4765	L-Norleucine	(S)-Norleucine,alpha-Aminocaproic acid,(S)-2-Aminohexanoic acid	Influenza Virus , Endogenous Metabolite
	L-Norleucine ((S)-Norleucine) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.		Influenza Virus , Endogenous Metabolite
T67893	PTP1B-IN-22		Phosphatase
	PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes.		Phosphatase
T4739	Sodium creatine phosphate dibasic tetrahydrate	Creatine phosphate disodium salt tetrahydrate	Others , Endogenous Metabolite
	Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) mainly exists in the skeletal muscles of vertebrates. It is a substrate for the determination of creatine kinase and can be u...		Others , Endogenous Metabolite
T0156	Rocuronium bromide	ORG 9426,ORG 9426 (Bromide)	AChR
	Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeleta...		AChR
T3966	Tirasemtiv	CK-2017357	Others
	Tirasemtiv (CK-2017357)(CK 2017357) is a small-molecule fast-skeletal-troponin activator, with a potential treatment for muscle weakness and neuromuscular dysfunction.		Others